Used in organic synthesis as an intermediate for pharmaceuticals and bioactive compounds. Its structure supports the development of nitrogen-containing heterocyclic systems, often found in medicinal agents. Commonly employed in cross-coupling reactions to form C–C and C–N bonds, enabling the construction of complex isoquinoline derivatives. These derivatives are relevant in the research of central nervous system agents, antimicrobial compounds, and kinase inhibitors. Also utilized in the preparation of fluorescent probes and materials for optoelectronic applications due to the electron-deficient nature of the chloro-substituted ring.