Palmitoyl Ethanolamide-d4 is primarily used in research and development, particularly in the field of lipidomics and metabolic studies. It serves as a stable isotope-labeled internal standard for the quantification of Palmitoyl Ethanolamide (PEA) in biological samples using techniques like mass spectrometry. This helps in understanding the role of PEA in various physiological processes, including its anti-inflammatory and analgesic properties. Additionally, it aids in the study of endocannabinoid-like molecules and their interactions within the endocannabinoid system, contributing to advancements in pain management and neuroprotection research.