Pyridone 6 is widely used as a potent and selective inhibitor of Janus kinase 2 (JAK2), making it a valuable tool in biochemical and pharmacological research. It is particularly effective in studying signaling pathways involved in cell proliferation, apoptosis, and immune responses. Researchers utilize it to investigate the role of JAK2 in diseases such as myeloproliferative disorders, leukemia, and autoimmune conditions. Additionally, it serves as a key compound in the development of targeted therapies for cancer and inflammatory diseases, helping to identify potential drug candidates and understand their mechanisms of action. Its application extends to in vitro and in vivo studies, providing insights into the therapeutic potential of JAK2 inhibition.