WHI-P180 is primarily utilized in research settings, particularly in the study of cancer biology and signal transduction pathways. It functions as an inhibitor of JAK3, a kinase involved in immune cell signaling, making it a valuable tool for investigating the role of JAK3 in various cellular processes. Researchers employ WHI-P180 to explore its potential in suppressing the growth of certain cancer cells, especially those dependent on JAK3 activity. Additionally, it is used to study autoimmune diseases and inflammatory conditions where JAK3 signaling plays a critical role. Its application extends to preclinical studies aimed at developing targeted therapies for diseases associated with dysregulated JAK3 pathways.