Used primarily in Karl Fischer titration to determine the water content in various substances. It is essential in industries like pharmaceuticals, where precise moisture measurement is critical for product stability and quality control. In the food industry, it helps ensure the proper moisture levels in products, affecting shelf life and safety. Additionally, it is used in chemical manufacturing to monitor water content in raw materials and final products, ensuring consistency and compliance with specifications. The titrant-component is also applied in petroleum and cosmetics industries to maintain quality standards by accurately measuring trace amounts of water.