Used in cancer research to study the inhibition of Eph receptors, which play a role in tumor growth and angiogenesis. It is particularly valuable in understanding the signaling pathways involved in cancer progression and metastasis. Researchers utilize it to explore potential therapeutic strategies targeting EphB4, a receptor linked to various cancers. Its application extends to preclinical studies where it helps evaluate the efficacy of targeted treatments in reducing tumor development and improving patient outcomes.