N-Desethyl Sunitinib
97%
Reagent
Code: #124777
CAS Number
356068-97-8
blur_circular Chemical Specifications
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Molecular Information
Weight
370.42 g/mol
Formula
C₂₀H₂₃FN₄O₂
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Storage & Handling
Storage
-20℃
description Product Description
N-Desethyl Sunitinib is primarily recognized for its role in cancer research and treatment, particularly as a metabolite of Sunitinib, a well-known tyrosine kinase inhibitor. It is studied for its potential therapeutic effects in targeting various cancers, including renal cell carcinoma and gastrointestinal stromal tumors. Researchers investigate its efficacy in inhibiting angiogenesis and tumor growth by blocking specific receptor tyrosine kinases involved in cancer progression. Additionally, it is used in pharmacokinetic studies to understand the metabolism and clearance of Sunitinib, aiding in optimizing dosing strategies and reducing adverse effects in patients. Its application extends to biomarker analysis, where it helps assess patient response to Sunitinib therapy.
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