1-((2-(tert-Butyl)-4-(3-chlorophenyl)thiazol-5-yl)methyl)-3-(3-fluoro-4-(hydroxymethyl)phenyl)urea

98%

Reagent Code: #130445
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CAS Number 1933528-96-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 447.95 g/mol
Formula C₂₂H₂₃ClFN₃O₂S
thermostat Physical Properties
Boiling Point 600.1±55.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.330±0.06 g/cm3(Predicted)
Storage Room temperature, seal, dry

description Product Description

Used in pharmaceutical research as a potent inhibitor of specific kinases involved in inflammatory pathways, particularly studied for its potential in treating autoimmune diseases such as rheumatoid arthritis. Shows high selectivity for TYK2 (tyrosine kinase 2), modulating cytokine signaling linked to immune dysregulation. Demonstrates good oral bioavailability and brain penetration in preclinical models, making it a candidate for central nervous system-related inflammatory conditions. Also explored for psoriasis and lupus due to its ability to suppress IL-12 and IL-23 pathways. Currently in investigational stages, not yet approved for clinical use.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿18,980.00
inventory 5mg
10-20 days ฿12,650.00

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