3-(2,3-Dioxoindolin-1-yl)propanoic acid
95%
Reagent
Code: #130626
CAS Number
81250-90-0
blur_circular Chemical Specifications
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Molecular Information
Weight
219.19 g/mol
Formula
C₁₁H₉NO₄
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Registry Numbers
MDL Number
MFCD01082237
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Physical Properties
Boiling Point
453.3±47.0 °C(Predicted)
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Storage & Handling
Density
1.448±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of indirubin and indigo derivatives, which exhibit biological activity in anti-cancer and anti-inflammatory applications. Commonly employed in pharmaceutical research for developing kinase inhibitors, especially targeting cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3 (GSK-3). Also utilized in the preparation of bioactive molecules for studying neurodegenerative diseases and cell signaling pathways. Its structure serves as a scaffold in medicinal chemistry due to its ability to interact with ATP-binding sites in enzymes.
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