6-Cyclopentyl-2-((2,5-dimethylbenzyl)thio)-4-oxo-1,4-dihydropyrimidine-5-carbonitrile
98%
Reagent
Code: #131220
CAS Number
1383539-73-8
blur_circular Chemical Specifications
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Molecular Information
Weight
339.45 g/mol
Formula
C₁₉H₂₁N₃OS
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Storage & Handling
Storage
Room temperature, light-proof, inert gas
description Product Description
Used as a potent inhibitor of cyclin-dependent kinases (CDKs), particularly CDK2 and CDK4, making it a valuable compound in cancer research. It interferes with cell cycle progression by blocking the activity of these kinases, which are crucial for cell division and proliferation. Due to this mechanism, it has been widely employed in studies related to antitumor agents and the development of targeted cancer therapies. Its structure allows for high selectivity and binding affinity, making it a common scaffold in medicinal chemistry for optimizing kinase inhibitors. Also utilized in biochemical assays to study cell cycle regulation and apoptosis in various cancer cell lines.
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