tert-Butyl (2-bromo-4-fluorobenzyl)(methyl)carbamate
95%
Reagent
Code: #131603
CAS Number
2358751-43-4
blur_circular Chemical Specifications
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Molecular Information
Weight
318.18 g/mol
Formula
C₁₃H₁₇BrFNO₂
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Registry Numbers
MDL Number
MFCD31924896
thermostat
Physical Properties
Boiling Point
352.1±30.0 °C(Predicted)
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Storage & Handling
Density
1.348±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. Its structure allows for selective modifications in drug design, especially in creating analogs with improved metabolic stability. Commonly employed in medicinal chemistry for introducing the tert-butoxycarbonyl (Boc) protected amine functionality while maintaining halogen handles for further coupling reactions, such as cross-coupling via palladium catalysis. Also utilized in the preparation of protease inhibitors and targeted cancer therapies.
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