1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-fluoro-5-(trifluoromethyl)phenyl)ethan-1-one
98%
Reagent
Code: #133116
CAS Number
1337531-89-1
blur_circular Chemical Specifications
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Molecular Information
Weight
469.43 g/mol
Formula
C₂₄H₁₉F₄N₅O
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Registry Numbers
MDL Number
MFCD27977960
thermostat
Physical Properties
Melting Point
233-238 °C(dec.)
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Storage & Handling
Storage
-20°C, Sealed, Dry
description Product Description
Used as a key intermediate in the synthesis of selective kinase inhibitors, particularly in the development of anticancer agents. It plays a role in targeting tyrosine kinases involved in cell signaling pathways that drive tumor growth and proliferation. Due to its structural features, it enhances binding affinity and selectivity toward specific kinase targets, making it valuable in medicinal chemistry for designing drugs with improved efficacy and reduced off-target effects. Commonly employed in research settings for structure-activity relationship (SAR) studies to optimize drug candidates in oncology.
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