(2-AMINO-4-TRIFLUOROMETHYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
97%
Reagent
Code: #133430
CAS Number
579474-48-9
blur_circular Chemical Specifications
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Molecular Information
Weight
276.2549 g/mol
Formula
C₁₂H₁₅F₃N₂O₂
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Registry Numbers
MDL Number
MFCD09701248
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Physical Properties
Boiling Point
290.1±40.0 °C(Predicted)
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Storage & Handling
Density
1.289±0.06 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in medicinal chemistry due to the presence of both amine and trifluoromethyl functional groups, which enhance binding affinity and metabolic stability in drug molecules. Commonly employed in the preparation of active pharmaceutical ingredients (APIs) requiring selective aromatic substitution patterns. Its tert-butyl carbamate (Boc) protection allows for controlled deprotection during multi-step syntheses, making it valuable in solid-phase and solution-phase peptide-like assembly processes.
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