6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile
95%
Reagent
Code: #137013
CAS Number
848139-78-6
blur_circular Chemical Specifications
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Molecular Information
Weight
445.90 g/mol
Formula
C₂₄H₂₀ClN₅O₂
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Registry Numbers
MDL Number
MFCD12032114
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Physical Properties
Melting Point
236-238 °C
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Storage & Handling
Storage
2-8°C, dry and sealed from light
description Product Description
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in the development of compounds that inhibit abnormal signaling pathways in tumor cells, especially in non-small cell lung cancer and other solid tumors. Its structure enables selective binding to mutant forms of epidermal growth factor receptor (EGFR), making it valuable in creating drugs with improved efficacy and reduced side effects. Also employed in research settings to explore new oncology treatments and structure-activity relationships in kinase inhibitor design.
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