6-(1-Acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)nicotinamide

98%

Reagent Code: #138454
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CAS Number 1655504-04-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 427.5 g/mol
Formula C₂₆H₂₅N₃O₃
inventory_2 Storage & Handling
Storage 2-8°C, dry

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of selective kinase inhibitors, particularly targeting tyrosine kinases involved in inflammatory and oncogenic signaling pathways. Its structure supports high binding affinity to specific enzyme active sites, making it valuable in developing treatments for autoimmune diseases and certain cancers. Also employed in the design of covalent inhibitors due to the acryloyl group, which enables irreversible binding to cysteine residues in target proteins. Additionally, it serves as a building block in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿8,310.00
inventory 50mg
10-20 days ฿14,110.00
inventory 100mg
10-20 days ฿25,220.00
inventory 250mg
10-20 days ฿50,000.00

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