6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine hydrochloride
≥99%
Reagent
Code: #139046
CAS Number
2200214-93-1
blur_circular Chemical Specifications
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Molecular Information
Weight
388.72 g/mol
Formula
C₁₆H₂₀Cl₃N₅
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Storage & Handling
Storage
-20°C
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of selective kinase inhibitors, particularly those targeting JAK (Janus kinase) pathways. It shows potential in the development of treatments for inflammatory diseases, autoimmune disorders, and certain cancers due to its role in modulating cellular signaling. Its structure supports high binding affinity and selectivity, making it valuable in optimizing drug candidates for improved efficacy and reduced off-target effects. Also employed in structure-activity relationship (SAR) studies to enhance pharmacokinetic properties in novel therapeutics.
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