4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione

97%

Reagent Code: #139224
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CAS Number 253168-83-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 418.46 g/mol
Formula C₂₀H₂₂N₂O₆S
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used primarily as a key intermediate in the synthesis of Apremilast, a selective phosphodiesterase 4 (PDE4) inhibitor for treating inflammatory conditions such as plaque psoriasis and psoriatic arthritis. Its structure enables modulation of cyclic AMP levels, leading to reduced production of pro-inflammatory cytokines like TNF-α, IL-17, and IL-23. The 4-amino group allows for further derivatization, such as acetylation, to enhance the compound's pharmacological properties and selectivity. It is also utilized in research to develop novel small-molecule therapeutics targeting inflammatory pathways.

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿10,500.00

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