tert-Butyl (S)-3-amino-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate
98%
Reagent
Code: #141470
CAS Number
2212021-59-3
blur_circular Chemical Specifications
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Molecular Information
Weight
374.45 g/mol
Formula
C₂₀H₂₇FN₄O₂
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Storage & Handling
Storage
2-8°C, away from light, dry
description Product Description
Used as a key intermediate in the synthesis of Janus kinase (JAK) inhibitors, particularly in the development of pharmaceuticals targeting inflammatory and autoimmune diseases such as rheumatoid arthritis and psoriasis. Its chiral structure enables selective interaction with biological targets, enhancing drug efficacy and reducing off-target effects. The tert-butyl carbamate (Boc) group provides protection for the amine during multi-step synthesis, allowing controlled deprotection and further functionalization. This compound is valuable in medicinal chemistry for constructing complex heterocyclic systems with high stereochemical purity.
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