Used primarily in research settings for its selective inhibition of IKK-2 (IκB kinase-2), this compound plays a key role in modulating the NF-κB signaling pathway. It is widely applied in studies related to inflammation, immune response, and cancer due to its ability to suppress the activation of NF-κB, a transcription factor involved in cell survival and inflammatory processes. Researchers utilize it to investigate the downstream effects of NF-κB inhibition in various cell types, particularly in models of autoimmune diseases and tumor progression. Its selectivity makes it a valuable tool for distinguishing IKK-2-dependent pathways from other kinase-mediated signaling events.