3-bromo-1h-pyrazolo[3,4-d]pyrimidin-4-ol
95%
Reagent
Code: #144228
Alias
3-bromo-1.5-dihydro-4H-pyrazolo[3.4-D]pyrimidin-4-one; 3-bromo-1H-pyrazolo[3,4-d]pyrimidin-4-ol;
CAS Number
54738-73-7
blur_circular Chemical Specifications
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Molecular Information
Weight
215.01 g/mol
Formula
C₅H₃BrN₄O
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Registry Numbers
MDL Number
MFCD00835293
thermostat
Physical Properties
Melting Point
350℃
Boiling Point
473.096ºC
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Storage & Handling
Density
2.236 g/cm3
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in pharmaceutical research targeting cancer therapies. It serves as a building block for compounds that modulate protein kinases involved in cell signaling, proliferation, and apoptosis. Its structure allows for selective modification, enabling the development of potent and selective inhibitors for tyrosine kinases and other enzyme targets. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize drug candidates. Also utilized in the preparation of small molecule therapeutics in oncology and inflammatory disease research.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity | 94.5-100 |
| Appearance | SOLID |
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