5-Bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine
95%
Reagent
Code: #145789
CAS Number
22276-99-9
blur_circular Chemical Specifications
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Molecular Information
Weight
213.04 g/mol
Formula
C₆H₅BrN₄
thermostat
Physical Properties
Boiling Point
452.6°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Its structure allows for selective modification to target specific protein kinases involved in tumor growth and signal transduction pathways. Commonly employed in medicinal chemistry for generating libraries of compounds aimed at treating leukemia and other malignancies. Also utilized in the preparation of BTK (Bruton's tyrosine kinase) inhibitors for autoimmune diseases and hematological cancers. Shows utility in research settings for probing biological pathways due to its ability to mimic purine bases in nucleotide-binding sites.
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