5-Bromo-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
95%
Reagent
Code: #145797
CAS Number
22276-97-7
blur_circular Chemical Specifications
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Molecular Information
Weight
214.02 g/mol
Formula
C₆H₄BrN₃O
thermostat
Physical Properties
Boiling Point
462.7°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. It serves as a building block for compounds targeting protein kinases involved in cell signaling pathways, such as JAK and EGFR families. Its structure allows selective modification at multiple positions, enabling optimization of biological activity and pharmacokinetic properties in drug candidates. Commonly employed in medicinal chemistry for generating libraries of pyrrolopyrimidine derivatives with potential antitumor, anti-inflammatory, or antiviral activity.
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