4-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-ol
95%
Reagent
Code: #145809
CAS Number
196603-96-0
blur_circular Chemical Specifications
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Molecular Information
Weight
364.17 g/mol
Formula
C₁₅H₁₁BrFN₃O₂
thermostat
Physical Properties
Boiling Point
470.9°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in the development of pharmaceuticals that inhibit abnormal signaling pathways in tumor cells, especially in non-small cell lung cancer and other solid tumors. Its structure allows selective binding to mutant forms of epidermal growth factor receptor (EGFR), making it valuable in creating drugs with improved efficacy and reduced side effects. Commonly utilized in research and development of next-generation oncology treatments.
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