1-Boc-3-(5-Bromopyrimidin-2-yloxy)pyrrolidine
95%
Reagent
Code: #146000
CAS Number
914347-79-8
blur_circular Chemical Specifications
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Molecular Information
Weight
344.2 g/mol
Formula
C₁₃H₁₈BrN₃O₃
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Registry Numbers
MDL Number
MFCD08460369
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors. Its structure allows for selective coupling reactions, making it valuable in constructing complex heterocyclic systems found in bioactive molecules. Commonly employed in medicinal chemistry for optimizing drug candidates targeting oncology and inflammatory diseases. The Boc-protected amine enables controlled deprotection and further functionalization, facilitating stepwise synthesis in multi-step reaction sequences. The 5-bromopyrimidin-2-yl group serves as a reactive handle for palladium-catalyzed cross-coupling reactions with amines, alcohols, or other nucleophiles.
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