tert-Butyl (3-ethynylphenyl)carbamate
97%
Reagent
Code: #148414
CAS Number
185619-66-3
blur_circular Chemical Specifications
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Molecular Information
Weight
217.26 g/mol
Formula
C₁₃H₁₅NO₂
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Registry Numbers
MDL Number
MFCD14585306
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Physical Properties
Boiling Point
277°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry seal
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its alkyne functionality allows for efficient coupling reactions, such as click chemistry via copper-catalyzed azide-alkyne cycloaddition, enabling rapid assembly of complex structures for drug discovery. The tert-butyl carbamate (Boc) group serves as a protected amine, offering stability during synthetic transformations and easy deprotection under mild acidic conditions. This compound is valuable in building blocks for medicinal chemistry and in the preparation of labeled compounds for biochemical assays.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity (%) | 96.5-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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