tert-Butyl (pyrimidin-2-ylmethyl)carbamate
≥95%
Reagent
Code: #150237
CAS Number
1260843-26-2
blur_circular Chemical Specifications
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Molecular Information
Weight
209.24 g/mol
Formula
C₁₀H₁₅N₃O₂
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Registry Numbers
MDL Number
MFCD11617314
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Storage & Handling
Storage
Room temperature, sealed, dry
description Product Description
Used as a protected amine intermediate in the synthesis of pharmaceutical compounds, particularly pyrimidine-based structures in bioactive molecules such as kinase inhibitors. The tert-butoxycarbonyl (Boc) group protects the amino functionality at the pyrimidin-2-ylmethyl position, enabling selective modifications during drug design. This enhances control over reaction pathways and allows for the creation of analogs with improved metabolic stability and binding affinity. Commonly employed in medicinal chemistry for developing therapeutics targeting oncology, inflammatory diseases, antivirals, and central nervous system disorders.
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