tert-Butyl ((1-aminocyclobutyl)methyl)carbamate
97%
Reagent
Code: #150239
CAS Number
1403767-13-4
blur_circular Chemical Specifications
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Molecular Information
Weight
200.28 g/mol
Formula
C₁₀H₂₀N₂O₂
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Registry Numbers
MDL Number
MFCD23106332
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as a protected amine intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules where the cyclobutylamine moiety is required. The tert-butoxycarbonyl (Boc) group provides stability during multi-step reactions and can be easily removed under mild acidic conditions to reveal the primary amine for further derivatization. Commonly employed in medicinal chemistry for constructing peptidomimetics and kinase inhibitors. Its rigid cyclobutane ring contributes to conformational constraint, enhancing selectivity and metabolic stability in drug candidates.
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