5-Bromopyridine-3-sulfonylfluoride
98%
Reagent
Code: #155716
CAS Number
1373307-59-5
blur_circular Chemical Specifications
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Molecular Information
Weight
240.05 g/mol
Formula
C₅H₃BrFNO₂S
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of sulfonamide-based pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules. Its sulfonyl fluoride group readily reacts with nucleophiles, making it valuable in click chemistry and protein labeling applications. It is also employed in the preparation of covalent inhibitors due to its ability to form stable bonds with specific amino acid residues in enzymes. Widely utilized in medicinal chemistry for structure-activity relationship studies and targeted drug design.
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