2-(Fluoromethyl)-6-nitro-3-(o-tolyl)quinazolin-4(3H)-one
97%
Reagent
Code: #188311
CAS Number
56287-73-1
science Other reagents with same CAS 56287-73-1
blur_circular Chemical Specifications
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Molecular Information
Weight
313.28 g/mol
Formula
C₁₆H₁₂FN₃O₃
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Registry Numbers
MDL Number
MFCD01686018
thermostat
Physical Properties
Melting Point
156-158 °C
Boiling Point
488.8°C at 760 mmHg
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Storage & Handling
Density
1.39 g/mL
Storage
2-8°C, inert gas
description Product Description
Used as a key intermediate in the synthesis of fluorinated quinazoline derivatives with potential biological activity, particularly in the development of kinase inhibitors for cancer therapy. Its structure supports binding to ATP sites in enzymes involved in cell signaling pathways. Commonly applied in medicinal chemistry research for designing compounds with antitumor and anti-inflammatory properties. Also utilized in structure-activity relationship (SAR) studies to optimize potency and selectivity in drug candidates.
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