Vactosertib (TEW-7197)
10mM in DMSO
Reagent
Code: #245218
CAS Number
1352608-82-2
science Other reagents with same CAS 1352608-82-2
blur_circular Chemical Specifications
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Molecular Information
Weight
399.42 g/mol
Formula
C₂₂H₁₈FN₇
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Storage & Handling
Storage
-20°C
description Product Description
Used in cancer research, particularly in targeting the TGF-β signaling pathway, which plays a key role in tumor progression and metastasis. It shows potential in inhibiting the growth and spread of various cancer types, including breast, lung, and colorectal cancers. Often studied in combination with other anticancer agents to enhance therapeutic efficacy. Also investigated for its role in overcoming drug resistance and suppressing epithelial-to-mesenchymal transition (EMT), a process linked to cancer aggressiveness. Currently in preclinical and early clinical development stages.
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