Vandetanib
2mM in DMSO
Reagent
Code: #245246
CAS Number
443913-73-3
science Other reagents with same CAS 443913-73-3
blur_circular Chemical Specifications
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Molecular Information
Weight
475.35 g/mol
Formula
C₂₂H₂₄BrFN₄O₂
thermostat
Physical Properties
Melting Point
240-243 °C
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of medullary thyroid cancer, especially in cases where the cancer cannot be surgically removed or has spread to other parts of the body. It functions by inhibiting specific tyrosine kinases, including RET, VEGFR, and EGFR, which are involved in tumor growth and angiogenesis. By blocking these pathways, it helps slow down or stop the progression of the disease. It is taken orally and is often prescribed for patients with symptomatic or progressive disease. Its use requires careful monitoring due to potential side effects affecting the heart, lungs, and liver.
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