VX-11e is primarily used in research settings as a selective inhibitor of certain kinase enzymes involved in cellular signaling pathways. It has been explored for its potential in studying inflammatory responses and neurodegenerative processes due to its ability to modulate microglial activation. Its cell permeability and stability make it suitable for in vitro and in vivo studies aiming to understand disease mechanisms related to chronic inflammation and neuronal damage. Additionally, VX-11e serves as a tool compound in drug discovery to validate targets within signaling cascades associated with cancer and autoimmune disorders.