VER-50589 is a potent and selective inhibitor of the enzyme Aurora B kinase, which plays a critical role in cell division, particularly in chromosome alignment and cytokinesis. Due to its ability to disrupt mitotic progression, it has been primarily investigated for its anticancer properties. It induces polyploidy and apoptosis in tumor cells by blocking Aurora B activity, making it a candidate for use in oncology research, especially in studies targeting solid tumors and hematological malignancies. Its selectivity enhances its utility in preclinical models to understand mitotic regulation and evaluate therapeutic strategies involving kinase inhibition. VER-50589 is not used clinically but serves as a valuable tool compound in cancer drug discovery and mechanistic studies of cell cycle control.