N-[(4-ethoxy-3-methoxyphenyl)methyl]-N-methyl-2-(3-pyridinyl)-4-quinazolinamine

98%

Reagent Code: #245663
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CAS Number 853339-68-1

science Other reagents with same CAS 853339-68-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 400.5 g/mol
Formula C₂₄H₂₄N₄O₂
thermostat Physical Properties
Boiling Point 507.0±50.0 °C(Predicted)
inventory_2 Storage & Handling
Storage -20°C, Sealed, Dry

description Product Description

Used in research as a potent and selective inhibitor of tyrosine kinases, particularly targeting epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2). These receptors are involved in signaling pathways that regulate cell proliferation and survival, making the compound valuable in studies of cancer biology. It has shown promise in preclinical models for inhibiting the growth of tumor cells, especially in non-small cell lung cancer and breast cancer. Its ability to cross the blood-brain barrier also makes it useful in investigating central nervous system metastases. Commonly employed in biochemical assays to elucidate kinase-dependent cellular mechanisms and as a lead compound in the development of targeted anticancer therapies.

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Size Availability Unit Price Quantity
inventory 1mg
10-20 days ฿2,190.00
inventory 25mg
10-20 days ฿35,180.00
inventory 5mg
10-20 days ฿8,790.00

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N-[(4-ethoxy-3-methoxyphenyl)methyl]-N-methyl-2-(3-pyridinyl)-4-quinazolinamine
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Used in research as a potent and selective inhibitor of tyrosine kinases, particularly targeting epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2). These receptors are involved in signaling pathways that regulate cell proliferation and survival, making the compound valuable in studies of cancer biology. It has shown promise in preclinical models for inhibiting the growth of tumor cells, especially in non-small cell lung cancer and breast cancer. Its ability to cr

Used in research as a potent and selective inhibitor of tyrosine kinases, particularly targeting epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2). These receptors are involved in signaling pathways that regulate cell proliferation and survival, making the compound valuable in studies of cancer biology. It has shown promise in preclinical models for inhibiting the growth of tumor cells, especially in non-small cell lung cancer and breast cancer. Its ability to cross the blood-brain barrier also makes it useful in investigating central nervous system metastases. Commonly employed in biochemical assays to elucidate kinase-dependent cellular mechanisms and as a lead compound in the development of targeted anticancer therapies.

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