Zanubrutinib
10mM in DMSO
Reagent
Code: #246440
CAS Number
1691249-45-2
science Other reagents with same CAS 1691249-45-2
blur_circular Chemical Specifications
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Molecular Information
Weight
471.55 g/mol
Formula
C₂₇H₂₉N₅O₃
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Storage & Handling
Storage
-20°C
description Product Description
Used in the treatment of certain B-cell malignancies, including mantle cell lymphoma and chronic lymphocytic leukemia. It functions as a selective inhibitor of Bruton's tyrosine kinase (BTK), a key enzyme in B-cell receptor signaling. By blocking BTK, it interferes with the survival, proliferation, and migration of malignant B-cells. Administered orally, it offers a targeted therapy option with potentially fewer off-target effects compared to earlier BTK inhibitors. Currently approved for use in several countries, it is part of ongoing research for additional hematologic cancer indications.
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