TC-E 5001 is primarily utilized in neuroscience research as a potent and selective inhibitor of the enzyme monoacylglycerol lipase (MAGL). By inhibiting MAGL, it increases the levels of 2-arachidonoylglycerol (2-AG), an endocannabinoid that plays a significant role in modulating synaptic transmission and neuroinflammation. This property makes it a valuable tool for studying the endocannabinoid system and its implications in various neurological disorders, such as pain, anxiety, and neurodegenerative diseases. Researchers also explore its potential therapeutic applications in conditions where enhancing endocannabinoid signaling could be beneficial.