RS4317 (Lonapalene) is primarily used in dermatology for its anti-inflammatory and antiproliferative properties. It has been investigated for the treatment of psoriasis, a chronic skin condition characterized by rapid skin cell growth and inflammation. The compound works by inhibiting the enzyme 5-lipoxygenase, which plays a key role in the inflammatory process, thereby reducing symptoms such as redness, scaling, and plaque formation. Additionally, it has shown potential in managing other inflammatory skin disorders, offering a therapeutic option for patients who may not respond well to conventional treatments. Its application extends to research settings, where it is studied for its mechanisms of action and potential use in broader inflammatory conditions. It is typically formulated as a cream or gel for topical application.