PepOil™ Pal-GHK (Palmitoyl Tripeptide-1, Oil-Soluble, 1000ppm)

Cosmetics Code: 254289

Oil-soluble Palmitoyl Tripeptide-1 liquid concentrate for wrinkle-care, firming, lip-care, facial oil, balm, and oil-serum formulations.

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Pep-Oil™ Pal-GHK (Palmitoyl Tripeptide-1, Oil-Soluble) is an oil-compatible liquid concentrate of Palmitoyl Tripeptide-1, also known as Pal-GHK, designed for leave-on anti-aging, lip-care, facial oil, balm, and oil-serum formulations.

Palmitoyl Tripeptide-1 is the palmitoylated form of the GHK tripeptide sequence. The palmitoyl chain improves lipid affinity, making this format useful when the formulator wants a peptide active in an oil phase, anhydrous base, balm, or emulsion oil phase rather than a water/glycol peptide solution.

This concentrate contains 0.1% Palmitoyl Tripeptide-1 active in an oil-soluble liquid format. It is intended for visible wrinkle-care, matrix-support, skin-smoothing, lip-line, and firmness concepts while keeping the peptide easier to incorporate into lipophilic systems.

Product Description: Palmitoyl Tripeptide-1 is commonly used as a matrikine-style signal peptide for collagen- and glycosaminoglycan-related anti-aging concepts. In formulation practice, it is used when the finished product needs support for the appearance of fine lines, wrinkle depth, skin smoothness, firmness, and elasticity. The evidence base is strongest for cosmetic appearance endpoints and formulation use; claims should remain cosmetic and should not be written as wound-healing, tissue-repair, or medical-regeneration claims.

Evidence / formulation context Relevant endpoints Practical implication
Human cosmetic use Wrinkle appearance, roughness, firmness, and texture endpoints reported for Palmitoyl Tripeptide-1-containing systems Supports anti-aging, smoothing, lip-line, and firmness product concept
Fibroblast / matrix rationale Collagen- and matrix-support signaling associated with the Pal-GHK sequence Useful in formulas targeting mature, photoaged, or texture-impaired skin appearance
Oil-soluble format Lipophilic handling, oil-phase compatibility, and easier use in balms, sticks, oils, and emulsions Preferred when water-soluble peptide concentrates are not suitable for the product base

Usage: Suitable for anti-aging creams, lotions, facial oils, oil-serums, lip balms, lipsticks, eye-area products, neck creams, body butter, and oil-rich hybrid skincare/makeup formulas.

Mixing method:

- Add into the oil phase or post-emulsification oil phase during cool-down.

- Avoid heating above 40°C; prolonged heat, strong light, and strong oxidizing systems can reduce peptide performance.

- For emulsions, add after the main emulsion has cooled and mix until uniform. For anhydrous oils, balms, and sticks, blend into the oil phase at the lowest practical temperature.

- Recommended finished-formula pH for emulsion systems: approximately pH 3.5-6.5.

Usage rate: 2.5-10% of this 0.1% concentrate (delivers approximately 0.0025-0.01% Palmitoyl Tripeptide-1 active). Typical: 5% concentrate delivers approximately 0.005% active.

Product characteristics: Colorless to pale yellow clear or slightly hazy oil-soluble liquid.

Solubility: Oil-soluble / oil-dispersible. Designed for oil phase, oil-serum, balm, stick, and emulsion systems where an oil-compatible peptide format is preferred.

Storage: Store refrigerated at 1-10°C, sealed, and protected from light. Bring to room temperature before weighing if viscosity increases during cold storage.


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Test Name Specification
Appearance Yellow oily liquid
Odor Nearly odorless
Palmitoyl Tripeptide-1 Content 950-1050ppm


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PepOil™ Pal-GHK (Palmitoyl Tripeptide-1, Oil-Soluble, 1000ppm)

Oil-soluble Palmitoyl Tripeptide-1 liquid concentrate for wrinkle-care, firming, lip-care, facial oil, balm, and oil-serum formulations.

Pep-Oil™ Pal-GHK (Palmitoyl Tripeptide-1, Oil-Soluble) is an oil-compatible liquid concentrate of Palmitoyl Tripeptide-1, also known as Pal-GHK, designed for leave-on anti-aging, lip-care, facial oil, balm, and oil-serum formulations.

Palmitoyl Tripeptide-1 is the palmitoylated form of the GHK tripeptide sequence. The palmitoyl chain improves lipid affinity, making this format useful when the formulator wants a peptide active in an oil phase, anhydrous base, balm, or emulsion oil phase rather than a water/glycol peptide solution.

This concentrate contains 0.1% Palmitoyl Tripeptide-1 active in an oil-soluble liquid format. It is intended for visible wrinkle-care, matrix-support, skin-smoothing, lip-line, and firmness concepts while keeping the peptide easier to incorporate into lipophilic systems.

Product Description: Palmitoyl Tripeptide-1 is commonly used as a matrikine-style signal peptide for collagen- and glycosaminoglycan-related anti-aging concepts. In formulation practice, it is used when the finished product needs support for the appearance of fine lines, wrinkle depth, skin smoothness, firmness, and elasticity. The evidence base is strongest for cosmetic appearance endpoints and formulation use; claims should remain cosmetic and should not be written as wound-healing, tissue-repair, or medical-regeneration claims.

Evidence / formulation context Relevant endpoints Practical implication
Human cosmetic use Wrinkle appearance, roughness, firmness, and texture endpoints reported for Palmitoyl Tripeptide-1-containing systems Supports anti-aging, smoothing, lip-line, and firmness product concept
Fibroblast / matrix rationale Collagen- and matrix-support signaling associated with the Pal-GHK sequence Useful in formulas targeting mature, photoaged, or texture-impaired skin appearance
Oil-soluble format Lipophilic handling, oil-phase compatibility, and easier use in balms, sticks, oils, and emulsions Preferred when water-soluble peptide concentrates are not suitable for the product base

Usage: Suitable for anti-aging creams, lotions, facial oils, oil-serums, lip balms, lipsticks, eye-area products, neck creams, body butter, and oil-rich hybrid skincare/makeup formulas.

Mixing method:

- Add into the oil phase or post-emulsification oil phase during cool-down.

- Avoid heating above 40°C; prolonged heat, strong light, and strong oxidizing systems can reduce peptide performance.

- For emulsions, add after the main emulsion has cooled and mix until uniform. For anhydrous oils, balms, and sticks, blend into the oil phase at the lowest practical temperature.

- Recommended finished-formula pH for emulsion systems: approximately pH 3.5-6.5.

Usage rate: 2.5-10% of this 0.1% concentrate (delivers approximately 0.0025-0.01% Palmitoyl Tripeptide-1 active). Typical: 5% concentrate delivers approximately 0.005% active.

Product characteristics: Colorless to pale yellow clear or slightly hazy oil-soluble liquid.

Solubility: Oil-soluble / oil-dispersible. Designed for oil phase, oil-serum, balm, stick, and emulsion systems where an oil-compatible peptide format is preferred.

Storage: Store refrigerated at 1-10°C, sealed, and protected from light. Bring to room temperature before weighing if viscosity increases during cold storage.

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