Used in clinical and research laboratories to quantify abnormal prothrombin (PIVKA-II), which is elevated in vitamin K deficiency and certain liver diseases, particularly hepatocellular carcinoma (HCC). The kit enables early detection and monitoring of HCC, especially in high-risk patients with chronic liver disease. It is also applied in studies investigating vitamin K metabolism and coagulation disorders. Due to its high sensitivity and specificity, it serves as a valuable tool in differential diagnosis of liver tumors and in evaluating the effectiveness of anticoagulant therapies involving vitamin K antagonists.