Acid-apeg8-acid n-c3-maleimide

95%

Reagent Code: #107506
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CAS Number 2100306-52-1

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scatter_plot Molecular Information
Weight 664.7 g/mol
Formula C₂₉H₄₈N₂O₁₅
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MDL Number MFCD29912655
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used in bioconjugation and drug delivery systems, it serves as a linker molecule for attaching therapeutic agents to targeting moieties like antibodies or peptides. Its maleimide group reacts selectively with thiol groups, enabling stable covalent bonds with cysteine residues in proteins or peptides. This property is particularly useful in antibody-drug conjugates (ADCs) for cancer therapy, where it ensures precise delivery of cytotoxic drugs to cancer cells. Additionally, it is employed in polymer chemistry to modify surfaces or create functionalized materials for biomedical applications. Its water-soluble PEG (polyethylene glycol) segment enhances biocompatibility and reduces immunogenicity, making it suitable for in vivo use.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿57,393.00
Acid-apeg8-acid n-c3-maleimide
Used in bioconjugation and drug delivery systems, it serves as a linker molecule for attaching therapeutic agents to targeting moieties like antibodies or peptides. Its maleimide group reacts selectively with thiol groups, enabling stable covalent bonds with cysteine residues in proteins or peptides. This property is particularly useful in antibody-drug conjugates (ADCs) for cancer therapy, where it ensures precise delivery of cytotoxic drugs to cancer cells. Additionally, it is employed in polymer chemistry to modify surfaces or create functionalized materials for biomedical applications. Its water-soluble PEG (polyethylene glycol) segment enhances biocompatibility and reduces immunogenicity, making it suitable for in vivo use.
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