4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid
≥98%
Reagent
Code: #118657
CAS Number
64987-82-2
blur_circular Chemical Specifications
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Molecular Information
Weight
237.26 g/mol
Formula
C₁₂H₁₅NO₄
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Registry Numbers
MDL Number
MFCD03093740
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Physical Properties
Melting Point
91°C(lit.)
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in bioconjugation and protein labeling, this compound serves as a linker in the development of antibody-drug conjugates (ADCs) and other therapeutic molecules. Its maleimide group reacts selectively with thiol groups in cysteine residues, enabling stable covalent attachment to proteins or peptides. This property is valuable in drug delivery systems, where precise targeting and controlled release are essential. Additionally, it finds applications in the preparation of affinity chromatography resins, aiding in the purification of biomolecules. Its cyclohexane structure provides rigidity, enhancing stability in various biochemical environments.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to almost white powder to crystal |
| Purity (%) | 97.5-100% |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
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