Maleimido-mono-amide-DOTA is widely used in the field of radiopharmaceuticals and molecular imaging. Its primary application is in the conjugation of biomolecules, such as antibodies, peptides, or proteins, for targeted imaging and therapy. The maleimide group allows for efficient and selective attachment to thiol-containing molecules, while the DOTA moiety enables chelation of radionuclides, such as lutetium-177 or gallium-68, for diagnostic and therapeutic purposes. This makes it a valuable tool in the development of radiopharmaceuticals for cancer diagnosis and treatment, particularly in targeted radiotherapy and positron emission tomography (PET) imaging. Additionally, it is utilized in research for studying biological processes and drug delivery systems due to its ability to create stable and specific conjugates.