SKF-86002 dihydrochloride is primarily used in pharmacological research as a potent and selective inhibitor of p38 MAP kinase. This enzyme plays a critical role in cellular responses to stress and inflammation, making the compound valuable in studying inflammatory diseases such as arthritis, asthma, and chronic obstructive pulmonary disease (COPD). Researchers utilize it to explore the mechanisms underlying these conditions and to evaluate potential therapeutic strategies targeting p38 MAP kinase pathways. Additionally, it aids in understanding the role of this kinase in cancer progression, as p38 MAP kinase is implicated in tumor growth and metastasis. Its application extends to neuroinflammatory studies, where it helps investigate the role of inflammation in neurodegenerative disorders like Alzheimer's disease.