Used in biomedical research to measure cyclic guanosine monophosphate (cGMP) levels in mouse samples. This kit enables researchers to quantify cGMP, a key secondary messenger involved in various signaling pathways, including those related to cardiovascular function, vision, and neuronal activity. It is commonly applied in studies investigating nitric oxide signaling, as cGMP production is stimulated by nitric oxide through activation of guanylate cyclase. The ELISA format allows for sensitive and specific detection of cGMP in tissue homogenates, cell lysates, and biological fluids such as plasma or urine. Widely used in pharmacological and physiological research to assess the effects of drugs, hormones, or genetic modifications on intracellular cGMP concentrations in mouse models.