Trans-ACPD is primarily used in neuroscience research as a selective agonist for metabotropic glutamate receptors (mGluRs). It helps in studying the role of these receptors in synaptic plasticity, learning, and memory processes. Additionally, it is utilized to investigate the mechanisms underlying neurological disorders such as epilepsy, Parkinson's disease, and schizophrenia, providing insights into potential therapeutic targets.