AMN082 dihydrochloride is primarily utilized in neuroscience research for its role as a selective metabotropic glutamate receptor 7 (mGluR7) allosteric agonist. It is extensively used to study the function and modulation of mGluR7 in the central nervous system, particularly in understanding its involvement in anxiety, depression, and other mood-related disorders. Researchers employ this compound to explore its potential therapeutic effects in modulating synaptic transmission and plasticity, which are critical in neurological and psychiatric conditions. Additionally, AMN082 dihydrochloride is used in preclinical studies to investigate its impact on behavioral responses and its potential as a target for developing novel treatments for CNS disorders. Its application is crucial in advancing the understanding of glutamate signaling pathways and their relevance to brain function and disease.