ADX88178 is primarily used in research settings to study its effects on the metabotropic glutamate receptor 4 (mGluR4). It acts as a positive allosteric modulator, enhancing the receptor's activity, which is significant in understanding neurological conditions. Researchers utilize ADX88178 to explore its potential in treating disorders such as Parkinson's disease, where mGluR4 modulation may help alleviate motor symptoms. Additionally, it is investigated for its role in managing anxiety and depression, as mGluR4 is implicated in mood regulation. The compound is also valuable in preclinical studies aimed at developing novel therapeutic agents targeting glutamate signaling pathways.