Copper Bisglycinate (28% Copper)

Food Code: 253146

Highly bioavailable chelated copper (bisglycinate) for immune, antioxidant and connective‑tissue support.

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Copper Bisglycinate (28% Copper)

Highly bioavailable chelated copper (bisglycinate) for immune, antioxidant and connective‑tissue support.

Copper Bisglycinate chelated copper bound to two glycine molecules is a highly bioavailable form of copper designed for gentle gastrointestinal tolerance and efficient absorption.


Benefit Typical study dose* Key human findings High-quality sources
Immune function support 1–2 mg elemental copper/day Adequate copper status supports neutrophil/T‑cell activity; copper compounds modulate pro‑inflammatory cytokines (↓ IL‑6, ↓ TNF‑α) in immune cells. PMC11944375; ODS
Antioxidant defense (SOD cofactor) 1–2 mg/day Copper is required for superoxide dismutase (SOD) activity; sufficient intake supports oxidative balance. ODS
Collagen & connective tissue ≈RDA to 2 mg/day Cofactor for lysyl oxidase that cross‑links collagen and elastin; adequate copper supports tissue integrity and wound healing. ODS
Energy metabolism & iron handling 1–2 mg/day Cofactor for cytochrome c oxidase (ATP production) and ceruloplasmin (iron mobilization); deficiency can lead to anemia‑like signs. ODS

*Doses refer to elemental copper from copper bisglycinate. Individual needs vary; consult a healthcare professional.



Mechanistic highlights

  1. Chelation with glycine: forms a neutral complex that supports absorption and gastrointestinal tolerance compared with inorganic salts.
  2. Redox enzymes: essential cofactor for Cu/Zn‑SOD and cytochrome c oxidase, supporting antioxidant defenses and mitochondrial respiration.
  3. Matrix enzymes: supports lysyl oxidase activity for collagen/elastin cross‑linking, relevant to connective tissue integrity.
  4. Immune modulation: influences cytokine signaling in immune cells (e.g., ↓ IL‑6, ↓ TNF‑α).


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