Used as a chiral building block in the synthesis of pharmaceuticals, particularly in the development of biologically active compounds where stereochemistry plays a critical role. Its trifluoromethyl group enhances metabolic stability and lipophilicity, making it valuable in drug design for central nervous system agents, enzyme inhibitors, and receptor modulators. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its rigid morpholine scaffold and electron-withdrawing substituent.