Ti3C2Tx (MXene) multilayer nanoflakes are widely used in energy storage applications, particularly in supercapacitors and lithium-ion batteries, due to their high electrical conductivity and large surface area. They enhance charge storage capacity and improve the overall efficiency of these devices. In the field of electromagnetic interference (EMI) shielding, these nanoflakes are incorporated into composites to create lightweight, flexible materials that effectively block electromagnetic radiation, making them suitable for use in electronics and aerospace industries. Additionally, Ti3C2Tx nanoflakes are employed in water purification systems. Their hydrophilic nature and ability to adsorb heavy metal ions and organic pollutants make them effective in filtering and cleaning contaminated water. In sensors, they are utilized for their high sensitivity to gases and chemicals, enabling the development of advanced environmental monitoring and biomedical sensing devices. Lastly, their unique properties are explored in catalysis, where they serve as supports or active components in various chemical reactions, including hydrogen evolution and CO2 reduction, contributing to sustainable energy solutions.